Abstract

We present a compressive video microscope based on structured illumination with incoherent light source. The source-side illumination coding scheme allows the emission photons being collected by the full aperture of the microscope objective, and thus is suitable for the fluorescence readout mode. A 2-step iterative reconstruction algorithm, termed BWISE, has been developed to address the mismatch between the illumination pattern size and the detector pixel size. Image sequences with a temporal compression ratio of 4:1 were demonstrated.

© 2016 Optical Society of America

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References

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  1. D. Buonomano, “The biology of time across different scales,” Nat. Chem. Biol. 3(10), 594–597 (2007).
    [Crossref] [PubMed]
  2. C. Hyeon and J. N. Onuchic, “Mechanical control of the directional stepping dynamics of the kinesin motor,” Proc. Natl. Acad. Sci.,  104(44), 17382–17387 (2007).
    [Crossref] [PubMed]
  3. M. Kim, M. Pan, Y. Gai, S. Pang, C. Han, C. Yang, and S. K. Y. Tang, “Optofluidic ultrahigh-throughput detection of fluorescent drops,” Lab Chip 15(6), 1417–1423 (2015).
    [Crossref] [PubMed]
  4. P. Llull, X. Liao, X. Yuan, J. Yang, D. Kittle, L. Carin, G. Sapiro, and D. J. Brady, “Coded aperture compressive temporal imaging,” Opt. Express 21(9), 10526–10545 (2013).
    [Crossref] [PubMed]
  5. M. G. Gustafsson, “Surpassing the lateral resolution limit by a factor of two using structured illumination microscopy,” J. Microsc. 198, 82–87 (2000).
    [Crossref] [PubMed]
  6. J. Mertz, “Optical sectioning microscopy with planar or structured illumination,” Nat. Methods 8, 811–819 (2011).
    [Crossref] [PubMed]
  7. J.W. Goodman, Introduction to Fourier Optics, 3rd ed. (Roberts and Company Publishers, 2005).
  8. X. Yuan, P. Llull, X. Liao, J. Yang, D. J. Brady, G. Sapiro, and L. Carin, “Low-cost compressive sensing for color video and depth,” in Proceedings of IEEE Conference on Computer Vision and Pattern Recognition, (Institute of Electrical and Electronics Engineers, Columbus, Ohio, 2014), pp. 3318–3325.
  9. Y. Hitomi, J. Gu, M. Gupta, T. Mitsunaga, and S.K. Nayar, “Video from a single coded exposure photograph using a learned over-complete dictionary,” in Proceedings of IEEE Conference on Computer Vision, (Institute of Electrical and ElectronicsEngineers, Barcelona, Spain, 2011), pp. 287–294.
  10. D. Reddy, A. Veeraraghavan, and R. Chellappa, “P2C2: Programmable pixel compressive camera for high speed imaging.,” in Proceedings of IEEE Conference on Computer Vision and Pattern Recognition, (Institute of Electrical and Electronics Engineers, Colorado, 2011), pp. 329–336.
  11. J. Bioucas-Dias and M. Figueiredo, “A new TwIST: two-step iterative shrinkage/thresholding algorithms for image restoration,” IEEE Trans. Image Process. 16(12), 2992–3004 (2007).
    [Crossref] [PubMed]
  12. X. Yuan, H. Jiang, G. Huang, and P. Wilford, “Lensless compressive imaging,” arXiv:1508.03498, (2015).
  13. X. Yuan, H. Jiang, G. Huang, and P. Wilford, “Compressive sensing via low-rank Gaussian mixture models,” arXiv:1508.06901, (2015).
  14. A. Beck and M. Teboulle, “A fast iterative shrinkage-thresholding algorithm for linear inverse problems,” SIAM J. Img. Sci. 2(1), 183–202 (2009).
    [Crossref]
  15. S. Boyd, N. Parikh, E. Chu, B. Peleato, and J. Eckstein, “Distributed optimization and statistical learning via the alternating direction method of multipliers,” Found. Trends Mach. Learn. 3(1), 1–122 (2011).
    [Crossref]
  16. X. Liao, H. Li, and L. Carin, “Generalized alternating projection for weighted-ℓ2,1 minimization with applications to model-based compressive sensing,” SIAM J. Img. Sci. 7(2), 797–823 (2014).
    [Crossref]
  17. J. Yang, X. Yuan, X. Liao, P. Llull, G. Sapiro, D. J. Brady, and L. Carin, “Video compressive sensing using Gaussian mixture models,” IEEE Trans. Image Process. 23(11), 4863–4878 (2014).
    [Crossref] [PubMed]
  18. T. M. Squires and S. R. Quake, “Microfluidics Fluid physics at the nanoliter,” Rev. Mod. Phys. 77(3), 977–1026 (2005).
    [Crossref]
  19. W. Jager, Y. Horiguchi, J. Shah, T. Hayashi, S. Awrey, K. M. Gust, B. A. Hadaschik, Y. Matsui, S. Anderson, R. H. Bell, S. Ettinger, A. I. So, M. E. Gleave, I. Lee, C. P. Dinney, M. Tachibana, D. J. McConkey, and P. C. Black, “Hiding in plain view: genetic profiling reveals decades old cross contamination of bladder cancer cell line KU7 with HeLa,” J Urol. 190(4), 1404–1409 (2013).
    [Crossref] [PubMed]
  20. J. H. Zhou, C. J. Rosser, M. Tanaka, M. Yang, E. Baranov, R. M. Hoffman, and W.F. Benedict, “Visualizing superficial human bladder cancer cell growth in vivo by green fluorescent protein expression,” Cancer Gene Ther. 9(8), 681–686 (2002).
    [Crossref] [PubMed]
  21. T. C. George, D. Basiji, B. E. Hall, D. H. Lynch, W. E. Ortyn, D. J. Perry, M. J. Seo, C. Zimmerman, and P. J. Morrissey, “Distinguishing modes of cell death using the ImageStream multispectral imaging flow cytometer,” Cytometry. A 59, 237–245 (2004).
    [Crossref] [PubMed]
  22. V. Studer, J. Bobin, M. Chahid, H. S. Mousavi, E. Candes, and M. Dahan, “Compressive fluorescence microscopy for biological and hyperspectral imaging”, Proc. Natl. Acad. Sci. USA 109(26), E1679–E1687 (2012).
    [Crossref] [PubMed]

2015 (1)

M. Kim, M. Pan, Y. Gai, S. Pang, C. Han, C. Yang, and S. K. Y. Tang, “Optofluidic ultrahigh-throughput detection of fluorescent drops,” Lab Chip 15(6), 1417–1423 (2015).
[Crossref] [PubMed]

2014 (2)

X. Liao, H. Li, and L. Carin, “Generalized alternating projection for weighted-ℓ2,1 minimization with applications to model-based compressive sensing,” SIAM J. Img. Sci. 7(2), 797–823 (2014).
[Crossref]

J. Yang, X. Yuan, X. Liao, P. Llull, G. Sapiro, D. J. Brady, and L. Carin, “Video compressive sensing using Gaussian mixture models,” IEEE Trans. Image Process. 23(11), 4863–4878 (2014).
[Crossref] [PubMed]

2013 (2)

W. Jager, Y. Horiguchi, J. Shah, T. Hayashi, S. Awrey, K. M. Gust, B. A. Hadaschik, Y. Matsui, S. Anderson, R. H. Bell, S. Ettinger, A. I. So, M. E. Gleave, I. Lee, C. P. Dinney, M. Tachibana, D. J. McConkey, and P. C. Black, “Hiding in plain view: genetic profiling reveals decades old cross contamination of bladder cancer cell line KU7 with HeLa,” J Urol. 190(4), 1404–1409 (2013).
[Crossref] [PubMed]

P. Llull, X. Liao, X. Yuan, J. Yang, D. Kittle, L. Carin, G. Sapiro, and D. J. Brady, “Coded aperture compressive temporal imaging,” Opt. Express 21(9), 10526–10545 (2013).
[Crossref] [PubMed]

2012 (1)

V. Studer, J. Bobin, M. Chahid, H. S. Mousavi, E. Candes, and M. Dahan, “Compressive fluorescence microscopy for biological and hyperspectral imaging”, Proc. Natl. Acad. Sci. USA 109(26), E1679–E1687 (2012).
[Crossref] [PubMed]

2011 (2)

J. Mertz, “Optical sectioning microscopy with planar or structured illumination,” Nat. Methods 8, 811–819 (2011).
[Crossref] [PubMed]

S. Boyd, N. Parikh, E. Chu, B. Peleato, and J. Eckstein, “Distributed optimization and statistical learning via the alternating direction method of multipliers,” Found. Trends Mach. Learn. 3(1), 1–122 (2011).
[Crossref]

2009 (1)

A. Beck and M. Teboulle, “A fast iterative shrinkage-thresholding algorithm for linear inverse problems,” SIAM J. Img. Sci. 2(1), 183–202 (2009).
[Crossref]

2007 (3)

J. Bioucas-Dias and M. Figueiredo, “A new TwIST: two-step iterative shrinkage/thresholding algorithms for image restoration,” IEEE Trans. Image Process. 16(12), 2992–3004 (2007).
[Crossref] [PubMed]

D. Buonomano, “The biology of time across different scales,” Nat. Chem. Biol. 3(10), 594–597 (2007).
[Crossref] [PubMed]

C. Hyeon and J. N. Onuchic, “Mechanical control of the directional stepping dynamics of the kinesin motor,” Proc. Natl. Acad. Sci.,  104(44), 17382–17387 (2007).
[Crossref] [PubMed]

2005 (1)

T. M. Squires and S. R. Quake, “Microfluidics Fluid physics at the nanoliter,” Rev. Mod. Phys. 77(3), 977–1026 (2005).
[Crossref]

2004 (1)

T. C. George, D. Basiji, B. E. Hall, D. H. Lynch, W. E. Ortyn, D. J. Perry, M. J. Seo, C. Zimmerman, and P. J. Morrissey, “Distinguishing modes of cell death using the ImageStream multispectral imaging flow cytometer,” Cytometry. A 59, 237–245 (2004).
[Crossref] [PubMed]

2002 (1)

J. H. Zhou, C. J. Rosser, M. Tanaka, M. Yang, E. Baranov, R. M. Hoffman, and W.F. Benedict, “Visualizing superficial human bladder cancer cell growth in vivo by green fluorescent protein expression,” Cancer Gene Ther. 9(8), 681–686 (2002).
[Crossref] [PubMed]

2000 (1)

M. G. Gustafsson, “Surpassing the lateral resolution limit by a factor of two using structured illumination microscopy,” J. Microsc. 198, 82–87 (2000).
[Crossref] [PubMed]

Anderson, S.

W. Jager, Y. Horiguchi, J. Shah, T. Hayashi, S. Awrey, K. M. Gust, B. A. Hadaschik, Y. Matsui, S. Anderson, R. H. Bell, S. Ettinger, A. I. So, M. E. Gleave, I. Lee, C. P. Dinney, M. Tachibana, D. J. McConkey, and P. C. Black, “Hiding in plain view: genetic profiling reveals decades old cross contamination of bladder cancer cell line KU7 with HeLa,” J Urol. 190(4), 1404–1409 (2013).
[Crossref] [PubMed]

Awrey, S.

W. Jager, Y. Horiguchi, J. Shah, T. Hayashi, S. Awrey, K. M. Gust, B. A. Hadaschik, Y. Matsui, S. Anderson, R. H. Bell, S. Ettinger, A. I. So, M. E. Gleave, I. Lee, C. P. Dinney, M. Tachibana, D. J. McConkey, and P. C. Black, “Hiding in plain view: genetic profiling reveals decades old cross contamination of bladder cancer cell line KU7 with HeLa,” J Urol. 190(4), 1404–1409 (2013).
[Crossref] [PubMed]

Baranov, E.

J. H. Zhou, C. J. Rosser, M. Tanaka, M. Yang, E. Baranov, R. M. Hoffman, and W.F. Benedict, “Visualizing superficial human bladder cancer cell growth in vivo by green fluorescent protein expression,” Cancer Gene Ther. 9(8), 681–686 (2002).
[Crossref] [PubMed]

Basiji, D.

T. C. George, D. Basiji, B. E. Hall, D. H. Lynch, W. E. Ortyn, D. J. Perry, M. J. Seo, C. Zimmerman, and P. J. Morrissey, “Distinguishing modes of cell death using the ImageStream multispectral imaging flow cytometer,” Cytometry. A 59, 237–245 (2004).
[Crossref] [PubMed]

Beck, A.

A. Beck and M. Teboulle, “A fast iterative shrinkage-thresholding algorithm for linear inverse problems,” SIAM J. Img. Sci. 2(1), 183–202 (2009).
[Crossref]

Bell, R. H.

W. Jager, Y. Horiguchi, J. Shah, T. Hayashi, S. Awrey, K. M. Gust, B. A. Hadaschik, Y. Matsui, S. Anderson, R. H. Bell, S. Ettinger, A. I. So, M. E. Gleave, I. Lee, C. P. Dinney, M. Tachibana, D. J. McConkey, and P. C. Black, “Hiding in plain view: genetic profiling reveals decades old cross contamination of bladder cancer cell line KU7 with HeLa,” J Urol. 190(4), 1404–1409 (2013).
[Crossref] [PubMed]

Benedict, W.F.

J. H. Zhou, C. J. Rosser, M. Tanaka, M. Yang, E. Baranov, R. M. Hoffman, and W.F. Benedict, “Visualizing superficial human bladder cancer cell growth in vivo by green fluorescent protein expression,” Cancer Gene Ther. 9(8), 681–686 (2002).
[Crossref] [PubMed]

Bioucas-Dias, J.

J. Bioucas-Dias and M. Figueiredo, “A new TwIST: two-step iterative shrinkage/thresholding algorithms for image restoration,” IEEE Trans. Image Process. 16(12), 2992–3004 (2007).
[Crossref] [PubMed]

Black, P. C.

W. Jager, Y. Horiguchi, J. Shah, T. Hayashi, S. Awrey, K. M. Gust, B. A. Hadaschik, Y. Matsui, S. Anderson, R. H. Bell, S. Ettinger, A. I. So, M. E. Gleave, I. Lee, C. P. Dinney, M. Tachibana, D. J. McConkey, and P. C. Black, “Hiding in plain view: genetic profiling reveals decades old cross contamination of bladder cancer cell line KU7 with HeLa,” J Urol. 190(4), 1404–1409 (2013).
[Crossref] [PubMed]

Bobin, J.

V. Studer, J. Bobin, M. Chahid, H. S. Mousavi, E. Candes, and M. Dahan, “Compressive fluorescence microscopy for biological and hyperspectral imaging”, Proc. Natl. Acad. Sci. USA 109(26), E1679–E1687 (2012).
[Crossref] [PubMed]

Boyd, S.

S. Boyd, N. Parikh, E. Chu, B. Peleato, and J. Eckstein, “Distributed optimization and statistical learning via the alternating direction method of multipliers,” Found. Trends Mach. Learn. 3(1), 1–122 (2011).
[Crossref]

Brady, D. J.

J. Yang, X. Yuan, X. Liao, P. Llull, G. Sapiro, D. J. Brady, and L. Carin, “Video compressive sensing using Gaussian mixture models,” IEEE Trans. Image Process. 23(11), 4863–4878 (2014).
[Crossref] [PubMed]

P. Llull, X. Liao, X. Yuan, J. Yang, D. Kittle, L. Carin, G. Sapiro, and D. J. Brady, “Coded aperture compressive temporal imaging,” Opt. Express 21(9), 10526–10545 (2013).
[Crossref] [PubMed]

X. Yuan, P. Llull, X. Liao, J. Yang, D. J. Brady, G. Sapiro, and L. Carin, “Low-cost compressive sensing for color video and depth,” in Proceedings of IEEE Conference on Computer Vision and Pattern Recognition, (Institute of Electrical and Electronics Engineers, Columbus, Ohio, 2014), pp. 3318–3325.

Buonomano, D.

D. Buonomano, “The biology of time across different scales,” Nat. Chem. Biol. 3(10), 594–597 (2007).
[Crossref] [PubMed]

Candes, E.

V. Studer, J. Bobin, M. Chahid, H. S. Mousavi, E. Candes, and M. Dahan, “Compressive fluorescence microscopy for biological and hyperspectral imaging”, Proc. Natl. Acad. Sci. USA 109(26), E1679–E1687 (2012).
[Crossref] [PubMed]

Carin, L.

X. Liao, H. Li, and L. Carin, “Generalized alternating projection for weighted-ℓ2,1 minimization with applications to model-based compressive sensing,” SIAM J. Img. Sci. 7(2), 797–823 (2014).
[Crossref]

J. Yang, X. Yuan, X. Liao, P. Llull, G. Sapiro, D. J. Brady, and L. Carin, “Video compressive sensing using Gaussian mixture models,” IEEE Trans. Image Process. 23(11), 4863–4878 (2014).
[Crossref] [PubMed]

P. Llull, X. Liao, X. Yuan, J. Yang, D. Kittle, L. Carin, G. Sapiro, and D. J. Brady, “Coded aperture compressive temporal imaging,” Opt. Express 21(9), 10526–10545 (2013).
[Crossref] [PubMed]

X. Yuan, P. Llull, X. Liao, J. Yang, D. J. Brady, G. Sapiro, and L. Carin, “Low-cost compressive sensing for color video and depth,” in Proceedings of IEEE Conference on Computer Vision and Pattern Recognition, (Institute of Electrical and Electronics Engineers, Columbus, Ohio, 2014), pp. 3318–3325.

Chahid, M.

V. Studer, J. Bobin, M. Chahid, H. S. Mousavi, E. Candes, and M. Dahan, “Compressive fluorescence microscopy for biological and hyperspectral imaging”, Proc. Natl. Acad. Sci. USA 109(26), E1679–E1687 (2012).
[Crossref] [PubMed]

Chellappa, R.

D. Reddy, A. Veeraraghavan, and R. Chellappa, “P2C2: Programmable pixel compressive camera for high speed imaging.,” in Proceedings of IEEE Conference on Computer Vision and Pattern Recognition, (Institute of Electrical and Electronics Engineers, Colorado, 2011), pp. 329–336.

Chu, E.

S. Boyd, N. Parikh, E. Chu, B. Peleato, and J. Eckstein, “Distributed optimization and statistical learning via the alternating direction method of multipliers,” Found. Trends Mach. Learn. 3(1), 1–122 (2011).
[Crossref]

Dahan, M.

V. Studer, J. Bobin, M. Chahid, H. S. Mousavi, E. Candes, and M. Dahan, “Compressive fluorescence microscopy for biological and hyperspectral imaging”, Proc. Natl. Acad. Sci. USA 109(26), E1679–E1687 (2012).
[Crossref] [PubMed]

Dinney, C. P.

W. Jager, Y. Horiguchi, J. Shah, T. Hayashi, S. Awrey, K. M. Gust, B. A. Hadaschik, Y. Matsui, S. Anderson, R. H. Bell, S. Ettinger, A. I. So, M. E. Gleave, I. Lee, C. P. Dinney, M. Tachibana, D. J. McConkey, and P. C. Black, “Hiding in plain view: genetic profiling reveals decades old cross contamination of bladder cancer cell line KU7 with HeLa,” J Urol. 190(4), 1404–1409 (2013).
[Crossref] [PubMed]

Eckstein, J.

S. Boyd, N. Parikh, E. Chu, B. Peleato, and J. Eckstein, “Distributed optimization and statistical learning via the alternating direction method of multipliers,” Found. Trends Mach. Learn. 3(1), 1–122 (2011).
[Crossref]

Ettinger, S.

W. Jager, Y. Horiguchi, J. Shah, T. Hayashi, S. Awrey, K. M. Gust, B. A. Hadaschik, Y. Matsui, S. Anderson, R. H. Bell, S. Ettinger, A. I. So, M. E. Gleave, I. Lee, C. P. Dinney, M. Tachibana, D. J. McConkey, and P. C. Black, “Hiding in plain view: genetic profiling reveals decades old cross contamination of bladder cancer cell line KU7 with HeLa,” J Urol. 190(4), 1404–1409 (2013).
[Crossref] [PubMed]

Figueiredo, M.

J. Bioucas-Dias and M. Figueiredo, “A new TwIST: two-step iterative shrinkage/thresholding algorithms for image restoration,” IEEE Trans. Image Process. 16(12), 2992–3004 (2007).
[Crossref] [PubMed]

Gai, Y.

M. Kim, M. Pan, Y. Gai, S. Pang, C. Han, C. Yang, and S. K. Y. Tang, “Optofluidic ultrahigh-throughput detection of fluorescent drops,” Lab Chip 15(6), 1417–1423 (2015).
[Crossref] [PubMed]

George, T. C.

T. C. George, D. Basiji, B. E. Hall, D. H. Lynch, W. E. Ortyn, D. J. Perry, M. J. Seo, C. Zimmerman, and P. J. Morrissey, “Distinguishing modes of cell death using the ImageStream multispectral imaging flow cytometer,” Cytometry. A 59, 237–245 (2004).
[Crossref] [PubMed]

Gleave, M. E.

W. Jager, Y. Horiguchi, J. Shah, T. Hayashi, S. Awrey, K. M. Gust, B. A. Hadaschik, Y. Matsui, S. Anderson, R. H. Bell, S. Ettinger, A. I. So, M. E. Gleave, I. Lee, C. P. Dinney, M. Tachibana, D. J. McConkey, and P. C. Black, “Hiding in plain view: genetic profiling reveals decades old cross contamination of bladder cancer cell line KU7 with HeLa,” J Urol. 190(4), 1404–1409 (2013).
[Crossref] [PubMed]

Goodman, J.W.

J.W. Goodman, Introduction to Fourier Optics, 3rd ed. (Roberts and Company Publishers, 2005).

Gu, J.

Y. Hitomi, J. Gu, M. Gupta, T. Mitsunaga, and S.K. Nayar, “Video from a single coded exposure photograph using a learned over-complete dictionary,” in Proceedings of IEEE Conference on Computer Vision, (Institute of Electrical and ElectronicsEngineers, Barcelona, Spain, 2011), pp. 287–294.

Gupta, M.

Y. Hitomi, J. Gu, M. Gupta, T. Mitsunaga, and S.K. Nayar, “Video from a single coded exposure photograph using a learned over-complete dictionary,” in Proceedings of IEEE Conference on Computer Vision, (Institute of Electrical and ElectronicsEngineers, Barcelona, Spain, 2011), pp. 287–294.

Gust, K. M.

W. Jager, Y. Horiguchi, J. Shah, T. Hayashi, S. Awrey, K. M. Gust, B. A. Hadaschik, Y. Matsui, S. Anderson, R. H. Bell, S. Ettinger, A. I. So, M. E. Gleave, I. Lee, C. P. Dinney, M. Tachibana, D. J. McConkey, and P. C. Black, “Hiding in plain view: genetic profiling reveals decades old cross contamination of bladder cancer cell line KU7 with HeLa,” J Urol. 190(4), 1404–1409 (2013).
[Crossref] [PubMed]

Gustafsson, M. G.

M. G. Gustafsson, “Surpassing the lateral resolution limit by a factor of two using structured illumination microscopy,” J. Microsc. 198, 82–87 (2000).
[Crossref] [PubMed]

Hadaschik, B. A.

W. Jager, Y. Horiguchi, J. Shah, T. Hayashi, S. Awrey, K. M. Gust, B. A. Hadaschik, Y. Matsui, S. Anderson, R. H. Bell, S. Ettinger, A. I. So, M. E. Gleave, I. Lee, C. P. Dinney, M. Tachibana, D. J. McConkey, and P. C. Black, “Hiding in plain view: genetic profiling reveals decades old cross contamination of bladder cancer cell line KU7 with HeLa,” J Urol. 190(4), 1404–1409 (2013).
[Crossref] [PubMed]

Hall, B. E.

T. C. George, D. Basiji, B. E. Hall, D. H. Lynch, W. E. Ortyn, D. J. Perry, M. J. Seo, C. Zimmerman, and P. J. Morrissey, “Distinguishing modes of cell death using the ImageStream multispectral imaging flow cytometer,” Cytometry. A 59, 237–245 (2004).
[Crossref] [PubMed]

Han, C.

M. Kim, M. Pan, Y. Gai, S. Pang, C. Han, C. Yang, and S. K. Y. Tang, “Optofluidic ultrahigh-throughput detection of fluorescent drops,” Lab Chip 15(6), 1417–1423 (2015).
[Crossref] [PubMed]

Hayashi, T.

W. Jager, Y. Horiguchi, J. Shah, T. Hayashi, S. Awrey, K. M. Gust, B. A. Hadaschik, Y. Matsui, S. Anderson, R. H. Bell, S. Ettinger, A. I. So, M. E. Gleave, I. Lee, C. P. Dinney, M. Tachibana, D. J. McConkey, and P. C. Black, “Hiding in plain view: genetic profiling reveals decades old cross contamination of bladder cancer cell line KU7 with HeLa,” J Urol. 190(4), 1404–1409 (2013).
[Crossref] [PubMed]

Hitomi, Y.

Y. Hitomi, J. Gu, M. Gupta, T. Mitsunaga, and S.K. Nayar, “Video from a single coded exposure photograph using a learned over-complete dictionary,” in Proceedings of IEEE Conference on Computer Vision, (Institute of Electrical and ElectronicsEngineers, Barcelona, Spain, 2011), pp. 287–294.

Hoffman, R. M.

J. H. Zhou, C. J. Rosser, M. Tanaka, M. Yang, E. Baranov, R. M. Hoffman, and W.F. Benedict, “Visualizing superficial human bladder cancer cell growth in vivo by green fluorescent protein expression,” Cancer Gene Ther. 9(8), 681–686 (2002).
[Crossref] [PubMed]

Horiguchi, Y.

W. Jager, Y. Horiguchi, J. Shah, T. Hayashi, S. Awrey, K. M. Gust, B. A. Hadaschik, Y. Matsui, S. Anderson, R. H. Bell, S. Ettinger, A. I. So, M. E. Gleave, I. Lee, C. P. Dinney, M. Tachibana, D. J. McConkey, and P. C. Black, “Hiding in plain view: genetic profiling reveals decades old cross contamination of bladder cancer cell line KU7 with HeLa,” J Urol. 190(4), 1404–1409 (2013).
[Crossref] [PubMed]

Huang, G.

X. Yuan, H. Jiang, G. Huang, and P. Wilford, “Lensless compressive imaging,” arXiv:1508.03498, (2015).

X. Yuan, H. Jiang, G. Huang, and P. Wilford, “Compressive sensing via low-rank Gaussian mixture models,” arXiv:1508.06901, (2015).

Hyeon, C.

C. Hyeon and J. N. Onuchic, “Mechanical control of the directional stepping dynamics of the kinesin motor,” Proc. Natl. Acad. Sci.,  104(44), 17382–17387 (2007).
[Crossref] [PubMed]

Jager, W.

W. Jager, Y. Horiguchi, J. Shah, T. Hayashi, S. Awrey, K. M. Gust, B. A. Hadaschik, Y. Matsui, S. Anderson, R. H. Bell, S. Ettinger, A. I. So, M. E. Gleave, I. Lee, C. P. Dinney, M. Tachibana, D. J. McConkey, and P. C. Black, “Hiding in plain view: genetic profiling reveals decades old cross contamination of bladder cancer cell line KU7 with HeLa,” J Urol. 190(4), 1404–1409 (2013).
[Crossref] [PubMed]

Jiang, H.

X. Yuan, H. Jiang, G. Huang, and P. Wilford, “Lensless compressive imaging,” arXiv:1508.03498, (2015).

X. Yuan, H. Jiang, G. Huang, and P. Wilford, “Compressive sensing via low-rank Gaussian mixture models,” arXiv:1508.06901, (2015).

Kim, M.

M. Kim, M. Pan, Y. Gai, S. Pang, C. Han, C. Yang, and S. K. Y. Tang, “Optofluidic ultrahigh-throughput detection of fluorescent drops,” Lab Chip 15(6), 1417–1423 (2015).
[Crossref] [PubMed]

Kittle, D.

Lee, I.

W. Jager, Y. Horiguchi, J. Shah, T. Hayashi, S. Awrey, K. M. Gust, B. A. Hadaschik, Y. Matsui, S. Anderson, R. H. Bell, S. Ettinger, A. I. So, M. E. Gleave, I. Lee, C. P. Dinney, M. Tachibana, D. J. McConkey, and P. C. Black, “Hiding in plain view: genetic profiling reveals decades old cross contamination of bladder cancer cell line KU7 with HeLa,” J Urol. 190(4), 1404–1409 (2013).
[Crossref] [PubMed]

Li, H.

X. Liao, H. Li, and L. Carin, “Generalized alternating projection for weighted-ℓ2,1 minimization with applications to model-based compressive sensing,” SIAM J. Img. Sci. 7(2), 797–823 (2014).
[Crossref]

Liao, X.

X. Liao, H. Li, and L. Carin, “Generalized alternating projection for weighted-ℓ2,1 minimization with applications to model-based compressive sensing,” SIAM J. Img. Sci. 7(2), 797–823 (2014).
[Crossref]

J. Yang, X. Yuan, X. Liao, P. Llull, G. Sapiro, D. J. Brady, and L. Carin, “Video compressive sensing using Gaussian mixture models,” IEEE Trans. Image Process. 23(11), 4863–4878 (2014).
[Crossref] [PubMed]

P. Llull, X. Liao, X. Yuan, J. Yang, D. Kittle, L. Carin, G. Sapiro, and D. J. Brady, “Coded aperture compressive temporal imaging,” Opt. Express 21(9), 10526–10545 (2013).
[Crossref] [PubMed]

X. Yuan, P. Llull, X. Liao, J. Yang, D. J. Brady, G. Sapiro, and L. Carin, “Low-cost compressive sensing for color video and depth,” in Proceedings of IEEE Conference on Computer Vision and Pattern Recognition, (Institute of Electrical and Electronics Engineers, Columbus, Ohio, 2014), pp. 3318–3325.

Llull, P.

J. Yang, X. Yuan, X. Liao, P. Llull, G. Sapiro, D. J. Brady, and L. Carin, “Video compressive sensing using Gaussian mixture models,” IEEE Trans. Image Process. 23(11), 4863–4878 (2014).
[Crossref] [PubMed]

P. Llull, X. Liao, X. Yuan, J. Yang, D. Kittle, L. Carin, G. Sapiro, and D. J. Brady, “Coded aperture compressive temporal imaging,” Opt. Express 21(9), 10526–10545 (2013).
[Crossref] [PubMed]

X. Yuan, P. Llull, X. Liao, J. Yang, D. J. Brady, G. Sapiro, and L. Carin, “Low-cost compressive sensing for color video and depth,” in Proceedings of IEEE Conference on Computer Vision and Pattern Recognition, (Institute of Electrical and Electronics Engineers, Columbus, Ohio, 2014), pp. 3318–3325.

Lynch, D. H.

T. C. George, D. Basiji, B. E. Hall, D. H. Lynch, W. E. Ortyn, D. J. Perry, M. J. Seo, C. Zimmerman, and P. J. Morrissey, “Distinguishing modes of cell death using the ImageStream multispectral imaging flow cytometer,” Cytometry. A 59, 237–245 (2004).
[Crossref] [PubMed]

Matsui, Y.

W. Jager, Y. Horiguchi, J. Shah, T. Hayashi, S. Awrey, K. M. Gust, B. A. Hadaschik, Y. Matsui, S. Anderson, R. H. Bell, S. Ettinger, A. I. So, M. E. Gleave, I. Lee, C. P. Dinney, M. Tachibana, D. J. McConkey, and P. C. Black, “Hiding in plain view: genetic profiling reveals decades old cross contamination of bladder cancer cell line KU7 with HeLa,” J Urol. 190(4), 1404–1409 (2013).
[Crossref] [PubMed]

McConkey, D. J.

W. Jager, Y. Horiguchi, J. Shah, T. Hayashi, S. Awrey, K. M. Gust, B. A. Hadaschik, Y. Matsui, S. Anderson, R. H. Bell, S. Ettinger, A. I. So, M. E. Gleave, I. Lee, C. P. Dinney, M. Tachibana, D. J. McConkey, and P. C. Black, “Hiding in plain view: genetic profiling reveals decades old cross contamination of bladder cancer cell line KU7 with HeLa,” J Urol. 190(4), 1404–1409 (2013).
[Crossref] [PubMed]

Mertz, J.

J. Mertz, “Optical sectioning microscopy with planar or structured illumination,” Nat. Methods 8, 811–819 (2011).
[Crossref] [PubMed]

Mitsunaga, T.

Y. Hitomi, J. Gu, M. Gupta, T. Mitsunaga, and S.K. Nayar, “Video from a single coded exposure photograph using a learned over-complete dictionary,” in Proceedings of IEEE Conference on Computer Vision, (Institute of Electrical and ElectronicsEngineers, Barcelona, Spain, 2011), pp. 287–294.

Morrissey, P. J.

T. C. George, D. Basiji, B. E. Hall, D. H. Lynch, W. E. Ortyn, D. J. Perry, M. J. Seo, C. Zimmerman, and P. J. Morrissey, “Distinguishing modes of cell death using the ImageStream multispectral imaging flow cytometer,” Cytometry. A 59, 237–245 (2004).
[Crossref] [PubMed]

Mousavi, H. S.

V. Studer, J. Bobin, M. Chahid, H. S. Mousavi, E. Candes, and M. Dahan, “Compressive fluorescence microscopy for biological and hyperspectral imaging”, Proc. Natl. Acad. Sci. USA 109(26), E1679–E1687 (2012).
[Crossref] [PubMed]

Nayar, S.K.

Y. Hitomi, J. Gu, M. Gupta, T. Mitsunaga, and S.K. Nayar, “Video from a single coded exposure photograph using a learned over-complete dictionary,” in Proceedings of IEEE Conference on Computer Vision, (Institute of Electrical and ElectronicsEngineers, Barcelona, Spain, 2011), pp. 287–294.

Onuchic, J. N.

C. Hyeon and J. N. Onuchic, “Mechanical control of the directional stepping dynamics of the kinesin motor,” Proc. Natl. Acad. Sci.,  104(44), 17382–17387 (2007).
[Crossref] [PubMed]

Ortyn, W. E.

T. C. George, D. Basiji, B. E. Hall, D. H. Lynch, W. E. Ortyn, D. J. Perry, M. J. Seo, C. Zimmerman, and P. J. Morrissey, “Distinguishing modes of cell death using the ImageStream multispectral imaging flow cytometer,” Cytometry. A 59, 237–245 (2004).
[Crossref] [PubMed]

Pan, M.

M. Kim, M. Pan, Y. Gai, S. Pang, C. Han, C. Yang, and S. K. Y. Tang, “Optofluidic ultrahigh-throughput detection of fluorescent drops,” Lab Chip 15(6), 1417–1423 (2015).
[Crossref] [PubMed]

Pang, S.

M. Kim, M. Pan, Y. Gai, S. Pang, C. Han, C. Yang, and S. K. Y. Tang, “Optofluidic ultrahigh-throughput detection of fluorescent drops,” Lab Chip 15(6), 1417–1423 (2015).
[Crossref] [PubMed]

Parikh, N.

S. Boyd, N. Parikh, E. Chu, B. Peleato, and J. Eckstein, “Distributed optimization and statistical learning via the alternating direction method of multipliers,” Found. Trends Mach. Learn. 3(1), 1–122 (2011).
[Crossref]

Peleato, B.

S. Boyd, N. Parikh, E. Chu, B. Peleato, and J. Eckstein, “Distributed optimization and statistical learning via the alternating direction method of multipliers,” Found. Trends Mach. Learn. 3(1), 1–122 (2011).
[Crossref]

Perry, D. J.

T. C. George, D. Basiji, B. E. Hall, D. H. Lynch, W. E. Ortyn, D. J. Perry, M. J. Seo, C. Zimmerman, and P. J. Morrissey, “Distinguishing modes of cell death using the ImageStream multispectral imaging flow cytometer,” Cytometry. A 59, 237–245 (2004).
[Crossref] [PubMed]

Quake, S. R.

T. M. Squires and S. R. Quake, “Microfluidics Fluid physics at the nanoliter,” Rev. Mod. Phys. 77(3), 977–1026 (2005).
[Crossref]

Reddy, D.

D. Reddy, A. Veeraraghavan, and R. Chellappa, “P2C2: Programmable pixel compressive camera for high speed imaging.,” in Proceedings of IEEE Conference on Computer Vision and Pattern Recognition, (Institute of Electrical and Electronics Engineers, Colorado, 2011), pp. 329–336.

Rosser, C. J.

J. H. Zhou, C. J. Rosser, M. Tanaka, M. Yang, E. Baranov, R. M. Hoffman, and W.F. Benedict, “Visualizing superficial human bladder cancer cell growth in vivo by green fluorescent protein expression,” Cancer Gene Ther. 9(8), 681–686 (2002).
[Crossref] [PubMed]

Sapiro, G.

J. Yang, X. Yuan, X. Liao, P. Llull, G. Sapiro, D. J. Brady, and L. Carin, “Video compressive sensing using Gaussian mixture models,” IEEE Trans. Image Process. 23(11), 4863–4878 (2014).
[Crossref] [PubMed]

P. Llull, X. Liao, X. Yuan, J. Yang, D. Kittle, L. Carin, G. Sapiro, and D. J. Brady, “Coded aperture compressive temporal imaging,” Opt. Express 21(9), 10526–10545 (2013).
[Crossref] [PubMed]

X. Yuan, P. Llull, X. Liao, J. Yang, D. J. Brady, G. Sapiro, and L. Carin, “Low-cost compressive sensing for color video and depth,” in Proceedings of IEEE Conference on Computer Vision and Pattern Recognition, (Institute of Electrical and Electronics Engineers, Columbus, Ohio, 2014), pp. 3318–3325.

Seo, M. J.

T. C. George, D. Basiji, B. E. Hall, D. H. Lynch, W. E. Ortyn, D. J. Perry, M. J. Seo, C. Zimmerman, and P. J. Morrissey, “Distinguishing modes of cell death using the ImageStream multispectral imaging flow cytometer,” Cytometry. A 59, 237–245 (2004).
[Crossref] [PubMed]

Shah, J.

W. Jager, Y. Horiguchi, J. Shah, T. Hayashi, S. Awrey, K. M. Gust, B. A. Hadaschik, Y. Matsui, S. Anderson, R. H. Bell, S. Ettinger, A. I. So, M. E. Gleave, I. Lee, C. P. Dinney, M. Tachibana, D. J. McConkey, and P. C. Black, “Hiding in plain view: genetic profiling reveals decades old cross contamination of bladder cancer cell line KU7 with HeLa,” J Urol. 190(4), 1404–1409 (2013).
[Crossref] [PubMed]

So, A. I.

W. Jager, Y. Horiguchi, J. Shah, T. Hayashi, S. Awrey, K. M. Gust, B. A. Hadaschik, Y. Matsui, S. Anderson, R. H. Bell, S. Ettinger, A. I. So, M. E. Gleave, I. Lee, C. P. Dinney, M. Tachibana, D. J. McConkey, and P. C. Black, “Hiding in plain view: genetic profiling reveals decades old cross contamination of bladder cancer cell line KU7 with HeLa,” J Urol. 190(4), 1404–1409 (2013).
[Crossref] [PubMed]

Squires, T. M.

T. M. Squires and S. R. Quake, “Microfluidics Fluid physics at the nanoliter,” Rev. Mod. Phys. 77(3), 977–1026 (2005).
[Crossref]

Studer, V.

V. Studer, J. Bobin, M. Chahid, H. S. Mousavi, E. Candes, and M. Dahan, “Compressive fluorescence microscopy for biological and hyperspectral imaging”, Proc. Natl. Acad. Sci. USA 109(26), E1679–E1687 (2012).
[Crossref] [PubMed]

Tachibana, M.

W. Jager, Y. Horiguchi, J. Shah, T. Hayashi, S. Awrey, K. M. Gust, B. A. Hadaschik, Y. Matsui, S. Anderson, R. H. Bell, S. Ettinger, A. I. So, M. E. Gleave, I. Lee, C. P. Dinney, M. Tachibana, D. J. McConkey, and P. C. Black, “Hiding in plain view: genetic profiling reveals decades old cross contamination of bladder cancer cell line KU7 with HeLa,” J Urol. 190(4), 1404–1409 (2013).
[Crossref] [PubMed]

Tanaka, M.

J. H. Zhou, C. J. Rosser, M. Tanaka, M. Yang, E. Baranov, R. M. Hoffman, and W.F. Benedict, “Visualizing superficial human bladder cancer cell growth in vivo by green fluorescent protein expression,” Cancer Gene Ther. 9(8), 681–686 (2002).
[Crossref] [PubMed]

Tang, S. K. Y.

M. Kim, M. Pan, Y. Gai, S. Pang, C. Han, C. Yang, and S. K. Y. Tang, “Optofluidic ultrahigh-throughput detection of fluorescent drops,” Lab Chip 15(6), 1417–1423 (2015).
[Crossref] [PubMed]

Teboulle, M.

A. Beck and M. Teboulle, “A fast iterative shrinkage-thresholding algorithm for linear inverse problems,” SIAM J. Img. Sci. 2(1), 183–202 (2009).
[Crossref]

Veeraraghavan, A.

D. Reddy, A. Veeraraghavan, and R. Chellappa, “P2C2: Programmable pixel compressive camera for high speed imaging.,” in Proceedings of IEEE Conference on Computer Vision and Pattern Recognition, (Institute of Electrical and Electronics Engineers, Colorado, 2011), pp. 329–336.

Wilford, P.

X. Yuan, H. Jiang, G. Huang, and P. Wilford, “Lensless compressive imaging,” arXiv:1508.03498, (2015).

X. Yuan, H. Jiang, G. Huang, and P. Wilford, “Compressive sensing via low-rank Gaussian mixture models,” arXiv:1508.06901, (2015).

Yang, C.

M. Kim, M. Pan, Y. Gai, S. Pang, C. Han, C. Yang, and S. K. Y. Tang, “Optofluidic ultrahigh-throughput detection of fluorescent drops,” Lab Chip 15(6), 1417–1423 (2015).
[Crossref] [PubMed]

Yang, J.

J. Yang, X. Yuan, X. Liao, P. Llull, G. Sapiro, D. J. Brady, and L. Carin, “Video compressive sensing using Gaussian mixture models,” IEEE Trans. Image Process. 23(11), 4863–4878 (2014).
[Crossref] [PubMed]

P. Llull, X. Liao, X. Yuan, J. Yang, D. Kittle, L. Carin, G. Sapiro, and D. J. Brady, “Coded aperture compressive temporal imaging,” Opt. Express 21(9), 10526–10545 (2013).
[Crossref] [PubMed]

X. Yuan, P. Llull, X. Liao, J. Yang, D. J. Brady, G. Sapiro, and L. Carin, “Low-cost compressive sensing for color video and depth,” in Proceedings of IEEE Conference on Computer Vision and Pattern Recognition, (Institute of Electrical and Electronics Engineers, Columbus, Ohio, 2014), pp. 3318–3325.

Yang, M.

J. H. Zhou, C. J. Rosser, M. Tanaka, M. Yang, E. Baranov, R. M. Hoffman, and W.F. Benedict, “Visualizing superficial human bladder cancer cell growth in vivo by green fluorescent protein expression,” Cancer Gene Ther. 9(8), 681–686 (2002).
[Crossref] [PubMed]

Yuan, X.

J. Yang, X. Yuan, X. Liao, P. Llull, G. Sapiro, D. J. Brady, and L. Carin, “Video compressive sensing using Gaussian mixture models,” IEEE Trans. Image Process. 23(11), 4863–4878 (2014).
[Crossref] [PubMed]

P. Llull, X. Liao, X. Yuan, J. Yang, D. Kittle, L. Carin, G. Sapiro, and D. J. Brady, “Coded aperture compressive temporal imaging,” Opt. Express 21(9), 10526–10545 (2013).
[Crossref] [PubMed]

X. Yuan, H. Jiang, G. Huang, and P. Wilford, “Lensless compressive imaging,” arXiv:1508.03498, (2015).

X. Yuan, P. Llull, X. Liao, J. Yang, D. J. Brady, G. Sapiro, and L. Carin, “Low-cost compressive sensing for color video and depth,” in Proceedings of IEEE Conference on Computer Vision and Pattern Recognition, (Institute of Electrical and Electronics Engineers, Columbus, Ohio, 2014), pp. 3318–3325.

X. Yuan, H. Jiang, G. Huang, and P. Wilford, “Compressive sensing via low-rank Gaussian mixture models,” arXiv:1508.06901, (2015).

Zhou, J. H.

J. H. Zhou, C. J. Rosser, M. Tanaka, M. Yang, E. Baranov, R. M. Hoffman, and W.F. Benedict, “Visualizing superficial human bladder cancer cell growth in vivo by green fluorescent protein expression,” Cancer Gene Ther. 9(8), 681–686 (2002).
[Crossref] [PubMed]

Zimmerman, C.

T. C. George, D. Basiji, B. E. Hall, D. H. Lynch, W. E. Ortyn, D. J. Perry, M. J. Seo, C. Zimmerman, and P. J. Morrissey, “Distinguishing modes of cell death using the ImageStream multispectral imaging flow cytometer,” Cytometry. A 59, 237–245 (2004).
[Crossref] [PubMed]

Cancer Gene Ther. (1)

J. H. Zhou, C. J. Rosser, M. Tanaka, M. Yang, E. Baranov, R. M. Hoffman, and W.F. Benedict, “Visualizing superficial human bladder cancer cell growth in vivo by green fluorescent protein expression,” Cancer Gene Ther. 9(8), 681–686 (2002).
[Crossref] [PubMed]

Cytometry. A (1)

T. C. George, D. Basiji, B. E. Hall, D. H. Lynch, W. E. Ortyn, D. J. Perry, M. J. Seo, C. Zimmerman, and P. J. Morrissey, “Distinguishing modes of cell death using the ImageStream multispectral imaging flow cytometer,” Cytometry. A 59, 237–245 (2004).
[Crossref] [PubMed]

Found. Trends Mach. Learn. (1)

S. Boyd, N. Parikh, E. Chu, B. Peleato, and J. Eckstein, “Distributed optimization and statistical learning via the alternating direction method of multipliers,” Found. Trends Mach. Learn. 3(1), 1–122 (2011).
[Crossref]

IEEE Trans. Image Process. (2)

J. Bioucas-Dias and M. Figueiredo, “A new TwIST: two-step iterative shrinkage/thresholding algorithms for image restoration,” IEEE Trans. Image Process. 16(12), 2992–3004 (2007).
[Crossref] [PubMed]

J. Yang, X. Yuan, X. Liao, P. Llull, G. Sapiro, D. J. Brady, and L. Carin, “Video compressive sensing using Gaussian mixture models,” IEEE Trans. Image Process. 23(11), 4863–4878 (2014).
[Crossref] [PubMed]

J Urol. (1)

W. Jager, Y. Horiguchi, J. Shah, T. Hayashi, S. Awrey, K. M. Gust, B. A. Hadaschik, Y. Matsui, S. Anderson, R. H. Bell, S. Ettinger, A. I. So, M. E. Gleave, I. Lee, C. P. Dinney, M. Tachibana, D. J. McConkey, and P. C. Black, “Hiding in plain view: genetic profiling reveals decades old cross contamination of bladder cancer cell line KU7 with HeLa,” J Urol. 190(4), 1404–1409 (2013).
[Crossref] [PubMed]

J. Microsc. (1)

M. G. Gustafsson, “Surpassing the lateral resolution limit by a factor of two using structured illumination microscopy,” J. Microsc. 198, 82–87 (2000).
[Crossref] [PubMed]

Lab Chip (1)

M. Kim, M. Pan, Y. Gai, S. Pang, C. Han, C. Yang, and S. K. Y. Tang, “Optofluidic ultrahigh-throughput detection of fluorescent drops,” Lab Chip 15(6), 1417–1423 (2015).
[Crossref] [PubMed]

Nat. Chem. Biol. (1)

D. Buonomano, “The biology of time across different scales,” Nat. Chem. Biol. 3(10), 594–597 (2007).
[Crossref] [PubMed]

Nat. Methods (1)

J. Mertz, “Optical sectioning microscopy with planar or structured illumination,” Nat. Methods 8, 811–819 (2011).
[Crossref] [PubMed]

Opt. Express (1)

Proc. Natl. Acad. Sci. (1)

C. Hyeon and J. N. Onuchic, “Mechanical control of the directional stepping dynamics of the kinesin motor,” Proc. Natl. Acad. Sci.,  104(44), 17382–17387 (2007).
[Crossref] [PubMed]

Proc. Natl. Acad. Sci. USA (1)

V. Studer, J. Bobin, M. Chahid, H. S. Mousavi, E. Candes, and M. Dahan, “Compressive fluorescence microscopy for biological and hyperspectral imaging”, Proc. Natl. Acad. Sci. USA 109(26), E1679–E1687 (2012).
[Crossref] [PubMed]

Rev. Mod. Phys. (1)

T. M. Squires and S. R. Quake, “Microfluidics Fluid physics at the nanoliter,” Rev. Mod. Phys. 77(3), 977–1026 (2005).
[Crossref]

SIAM J. Img. Sci. (2)

A. Beck and M. Teboulle, “A fast iterative shrinkage-thresholding algorithm for linear inverse problems,” SIAM J. Img. Sci. 2(1), 183–202 (2009).
[Crossref]

X. Liao, H. Li, and L. Carin, “Generalized alternating projection for weighted-ℓ2,1 minimization with applications to model-based compressive sensing,” SIAM J. Img. Sci. 7(2), 797–823 (2014).
[Crossref]

Other (6)

X. Yuan, H. Jiang, G. Huang, and P. Wilford, “Lensless compressive imaging,” arXiv:1508.03498, (2015).

X. Yuan, H. Jiang, G. Huang, and P. Wilford, “Compressive sensing via low-rank Gaussian mixture models,” arXiv:1508.06901, (2015).

J.W. Goodman, Introduction to Fourier Optics, 3rd ed. (Roberts and Company Publishers, 2005).

X. Yuan, P. Llull, X. Liao, J. Yang, D. J. Brady, G. Sapiro, and L. Carin, “Low-cost compressive sensing for color video and depth,” in Proceedings of IEEE Conference on Computer Vision and Pattern Recognition, (Institute of Electrical and Electronics Engineers, Columbus, Ohio, 2014), pp. 3318–3325.

Y. Hitomi, J. Gu, M. Gupta, T. Mitsunaga, and S.K. Nayar, “Video from a single coded exposure photograph using a learned over-complete dictionary,” in Proceedings of IEEE Conference on Computer Vision, (Institute of Electrical and ElectronicsEngineers, Barcelona, Spain, 2011), pp. 287–294.

D. Reddy, A. Veeraraghavan, and R. Chellappa, “P2C2: Programmable pixel compressive camera for high speed imaging.,” in Proceedings of IEEE Conference on Computer Vision and Pattern Recognition, (Institute of Electrical and Electronics Engineers, Colorado, 2011), pp. 329–336.

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Figures (9)

Fig. 1
Fig. 1 The forward model of structured illumination microscope. On the left we show the microscope measurement g, and on the right we depict the sensing process. The mathematical formulation is demonstrated in Equation (4). H is the point spread function matrix served as the blur kernel. { S i } i = 1 N T are the structured illumination matrix and { f i } i = 1 N T are the signal intensity from the object at different time slots. Each frame of the scene is first encoded via the structured illumination matrix and then the measurement is convoluted by the point spread function.
Fig. 2
Fig. 2 (a) The photo of the experimental setup. (b) The schematic of the setup. A 20 × 0.5 NA objective (bottom part) is used in the system. The coded aperture mask, placed at the conjugate image plane (middle-right part) in the illumination path. The step motion of the mask is synchronized with the camera (top part) acquisition.
Fig. 3
Fig. 3 The comparison of the reconstruction results of the simulated moving “UCF” logo dataset with different algorithms. The coded measurement is shown on the top-left. Each row shows one frame. Each row (2–7) shows one frame. From the first to the fifth columns are the truth, TwIST reconstruction, GAP reconstruction, pixel-wise TV reconstruction and proposed BWISE reconstruction, respectively.
Fig. 4
Fig. 4 Magnified reconstruction result showing the capability of proposed BWISE algorithm to reconstruct high frequency components. The reconstruction from the left to right is the truth, pixel-wise TV and proposed BWISE algorithm, respectively. It can be observed that the proposed BWISE recovers the high frequency components of the object.
Fig. 5
Fig. 5 Examples of the reconstructed images of the simulated moving beads dataset with illumination pattern size of 0.75, 1.5 and 6 µm. The top row shows the coded measurement and the bottom two rows demonstrate the reconstructed Frame 1 and Frame 6.
Fig. 6
Fig. 6 PSNR of the reconstructed images of the simulated moving beads dataset with different illumination pattern sizes, 0.75µm – 6µm. 10 trials are performed with different random masks.
Fig. 7
Fig. 7 Experimental reconstructions of the “UCF” logo with the hardware setup shown in Fig. 2. (a) Frames of the raw measurements without structured illumination at 40 frames/second, (b) Coded measurements with the structured illumination at 40 frames/second, (c) Reconstruction of high-speed frames at 160 frames/second.
Fig. 8
Fig. 8 Fluorescence imaging of two moving HeLa cells emulating imaging flow cytometry. (a) 20× microscope image of bright field (top) and fluorescence image (bottom). (b) Low frame rate (2 fps) measurement with structured illumination. (c) Image sequence reconstruction with high frame rate (8 fps). The circles with a diameter of 30µm were added in each frame to aid the visualization.
Fig. 9
Fig. 9 Reconstruction results of a static USAF-1951 resolution target. (a) Measurement from the experimental prototype in reflection mode. (b) The 4 reconstructed frames. (c) Zoom-in figure of the boxed area in (b). Notice that the highest resolution can be clearly identified from the intensity profile (c2).

Equations (17)

Equations on this page are rendered with MathJax. Learn more.

g ( x , y , t i ) = t i t i + Δ t [ h ( x x , y y ) S ( x , y , t ) f ( x , y , t ) d x d y ] d t ,
g ( x , y , t i ) = k = 1 N T h ( x x , y y ) S k ( x , y ) f k ( x , y ) d x d y ,
F k = [ f 11 ( k ) f 12 ( k ) f 1 n ( k ) f 21 ( k ) f 22 ( k ) f 2 n ( k ) f m 1 ( k ) f m 2 ( k ) f m n ( k ) ] ,
g = H ( [ S 1 S 2 S N T ] [ f 1 f 2 f N T ] ) ,
g ( x , t ) = f ( x , t ) S ( x s t ) h ( x x ) rect ( t t Δ t ) d x d t ,
g ^ ( u , v ) = H ( u ) sinc ( v Δ t ) f ^ ( u w , v s w ) S ^ ( w ) d w ,
H ( u ) = w ( p + u / 2 ) w * ( p u / 2 ) d p | w ( p ) | 2 d p ,
w ( u ) = { 1 , if λ u N A < 1 0 , otherwise
g = Af ,
f ^ = argmin f g Af 2 2 + τ R ( f ) ,
R ( f ) = { Tf 1 , T is a sparse basis , n t = 1 N T TV ( f n t ) , TV is imposed on each frame .
TV ( f n t ) = i , j m , n ( f i + 1 , j , n t f i , j , n t ) 2 + ( f i , j + 1 , n t f i , j n t ) 2
f ˜ k + 1 = f k + α A ( g A f k ) ,
f k + 1 = Denoising ( f ˜ k + 1 ) .
f k + 1 = f ˜ k + 1 D ˜ z k ,
z k + 1 = clip ( z k + 1 β D ˜ f k + 1 , γ 2 ) .
clip ( b , T ) : = { b b T T sign ( b ) b > T

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