Abstract

This paper proposes a label-free and spectrometer-free method for biological detection with high detecting resolution. Taking advantage of the optical properties of porous silicon microcavity, the refractive index changes caused by biological reaction can be detected by measuring the incident angle of the minimum reflected light intensity. Based on the above method, label-free eight-base pair DNA detection can be realized with a corresponding detection limit is as low as 87 nM. This method provides high detecting resolution at a low equipment cost, and can be further used to develop an advanced instrument for biological detection.

© 2015 Optical Society of America

Full Article  |  PDF Article
OSA Recommended Articles
Detection of Echinococcus granulosus antigen by a quantum dot/porous silicon optical biosensor

Yanyu Li, Zhenhong Jia, Guodong Lv, Hao Wen, Peng Li, Hongyan Zhang, and Jiajia Wang
Biomed. Opt. Express 8(7) 3458-3469 (2017)

Protease detection using a porous silicon based Bloch surface wave optical biosensor

Hong Qiao, Bin Guan, J. Justin Gooding, and Peter J Reece
Opt. Express 18(14) 15174-15182 (2010)

Photonic crystal nanobeam biosensors based on porous silicon

Gilberto A. Rodriguez, Petr Markov, Alyssa P. Cartwright, Moinul H. Choudhury, Francis O. Afzal, Tengfei Cao, Sami I. Halimi, Scott T. Retterer, Ivan I. Kravchenko, and Sharon M. Weiss
Opt. Express 27(7) 9536-9549 (2019)

References

  • View by:
  • |
  • |
  • |

  1. D. C. Tessier, S. Boughaba, M. Arbour, P. Roos, and G. Pan, “Improved surface sensing of DNA on gas-etched porous silicon,” Sens. Actuators B Chem. 120(1), 220–230 (2006).
    [Crossref]
  2. O. Meskini, A. Abdelghani, A. Tlili, R. Mgaieth, N. Jaffrezic-Renault, and C. Martelet, “Porous silicon as functionalized material for immunosensor application,” Talanta 71(3), 1430–1433 (2007).
    [Crossref] [PubMed]
  3. S. P. Low, K. A. Williams, L. T. Canham, and N. H. Voelcker, “Evaluation of mammalian cell adhesion on surface-modified porous silicon,” Biomaterials 27(26), 4538–4546 (2006).
    [Crossref] [PubMed]
  4. S. Chan, P. M. Fauchet, Y. Li, L. J. Rothberg, and B. L. Miller, “Porous Silicon Microcavities for Biosensing Applications,” Phys. Status Solidi A 182(1), 541–546 (2000).
    [Crossref]
  5. S. Chan, Y. Li, L. J. Rothberg, B. L. Miller, and P. M. Fauchet, “Nanoscale silicon microcavities for biosening,” Mater. Sci. Eng. C 15(1-2), 277–282 (2001).
    [Crossref]
  6. D. R. Huanca, D. S. Raimundo, and W. J. Salcedo, “Backside contact effect on the morphological and optical features of porous silicon photonic crystals,” Microelectronics J. 40(4-5), 744–748 (2009).
    [Crossref]
  7. X. Y. Lü, T. Xue, Z. H.Jia, H. W. Shao, S. B. Hou, and F. C. Zhang, “Design and Realization of Label-free Optical Immunosensor Based on Porous Silicon Microcavities,” In Society of Photo-Optical Instrumentation Engineers (SPIE) Conference Series, (Academic 2008), pp. 71571E–71571E.
  8. F. S. H. Krismastuti, S. Pace, and N. H. Voelcker, “Porous silicon resonant microcavity biosensor for matrix metalloproteinase detection,” Adv. Funct. Mater. 24(23), 3639–3650 (2014).
  9. H. Ouyang, L. A. Delouise, B. L. Miller, and P. M. Fauchet, “Label-free quantitative detection of protein using macroporous silicon photonic bandgap biosensors,” Anal. Chem. 79(4), 1502–1506 (2007).
    [Crossref] [PubMed]
  10. H. Zhang, Z. Jia, X. Lü, J. Hou, X. Liu, J. Ma, and J. Zhou, “Antifreeze protein detection using Rhodamine B as photoluminescence label in porous silicon,” Curr. Appl. Phys. 13(4), 736–742 (2013).
    [Crossref]
  11. I. A. Levitsky, W. B. Euler, N. Tokranova, and A. Rose, “Fluorescent polymer-porous silicon microcavity devices for explosive detection,” Appl. Phys. Lett. 90(4), 041904 (2007).
    [Crossref]
  12. Y. M. Lai, J. Wang, T. He, and S. Sun, “Improved Surface Enhanced Raman Scattering for Nanostructured Silver on Porous Silicon for Ultrasensitive Determination of 2, 4, 6-Trinitrotoluene,” Anal. Lett. 47(5), 833–842 (2014).
    [Crossref]
  13. S. Chan and P. M. Fauchet, “Tunable, narrow, and directional luminescence from porous silicon light emtting devices,” Appl. Phys. Lett. 75(2), 274–276 (1999).
    [Crossref]
  14. X. Lü, L. Chen, H. Zhang, J. Mo, F. Zhong, C. Lv, J. Ma, and Z. Jia, “Hybridization assay of insect antifreezing protein gene by novel multilayered porous silicon nucleic acid biosensor,” Biosens. Bioelectron. 39(1), 329–333 (2013).
    [Crossref] [PubMed]
  15. L. Pavesi, “Porous silicon dielectric multilayers and microcavities,” Riv. Nuovo Cim. 20(10), 1–76 (1997).
    [Crossref]
  16. L. De Stefano, L. Moretti, I. Rendina, and A. M. Rossi, “Porous silicon microcavities for optical hydrocarbons detection,” Sens. Actuators A Phys. 104(2), 179–182 (2003).
    [Crossref]
  17. L. D. Stefano, I. Rendina, L. Moretti, and A. M. Rossi, “Optical sensing of flammable substances using porous silicon microcavities,” Mater. Sci. Eng. B 100(3), 271–274 (2003).
    [Crossref]
  18. A. M. Giovannozzi, V. E. V. Ferrero, F. Pennecchi, S. J. Sadeghi, G. Gilardi, and A. M. Rossi, “P450-based porous silicon biosensor for arachidonic acid detection,” Biosens. Bioelectron. 28(1), 320–325 (2011).
    [Crossref] [PubMed]
  19. G. G. Rong and S. M. Weiss, “Biomolecule size‐dependent sensitivity of porous silicon sensors,” Phys. Status Solidi A 206(6), 1365–1368 (2009).
    [Crossref]
  20. H. Zhang, Z. Jia, X. Lü, J. Zhou, L. Chen, R. Liu, and J. Ma, “Porous silicon optical microcavity biosensor on silicon-on-insulator wafer for sensitive DNA detection,” Biosens. Bioelectron. 44, 89–94 (2013).
    [Crossref] [PubMed]
  21. G.G.Rong, J.D. Ryckman, R.L.Mernaugh, and S.M.Weiss, “Label-free porous silicon membrane waveguide for DNA sensing,” Appl. Phys. Lett. 93(16), 161109–161109, 1–3(2008).
    [Crossref]
  22. X. Lü, F. Zhong, Z. Jia, L. Chen, J. Ma, H. Zhang, Z. Cao, and J. Zhou, “Development of silicon-on-insulator-based nanoporous silicon photonic crystals for label-free DNA detection,” Opt. Eng. 52(6), 064401 (2013).
    [Crossref]

2014 (2)

F. S. H. Krismastuti, S. Pace, and N. H. Voelcker, “Porous silicon resonant microcavity biosensor for matrix metalloproteinase detection,” Adv. Funct. Mater. 24(23), 3639–3650 (2014).

Y. M. Lai, J. Wang, T. He, and S. Sun, “Improved Surface Enhanced Raman Scattering for Nanostructured Silver on Porous Silicon for Ultrasensitive Determination of 2, 4, 6-Trinitrotoluene,” Anal. Lett. 47(5), 833–842 (2014).
[Crossref]

2013 (4)

X. Lü, L. Chen, H. Zhang, J. Mo, F. Zhong, C. Lv, J. Ma, and Z. Jia, “Hybridization assay of insect antifreezing protein gene by novel multilayered porous silicon nucleic acid biosensor,” Biosens. Bioelectron. 39(1), 329–333 (2013).
[Crossref] [PubMed]

H. Zhang, Z. Jia, X. Lü, J. Hou, X. Liu, J. Ma, and J. Zhou, “Antifreeze protein detection using Rhodamine B as photoluminescence label in porous silicon,” Curr. Appl. Phys. 13(4), 736–742 (2013).
[Crossref]

H. Zhang, Z. Jia, X. Lü, J. Zhou, L. Chen, R. Liu, and J. Ma, “Porous silicon optical microcavity biosensor on silicon-on-insulator wafer for sensitive DNA detection,” Biosens. Bioelectron. 44, 89–94 (2013).
[Crossref] [PubMed]

X. Lü, F. Zhong, Z. Jia, L. Chen, J. Ma, H. Zhang, Z. Cao, and J. Zhou, “Development of silicon-on-insulator-based nanoporous silicon photonic crystals for label-free DNA detection,” Opt. Eng. 52(6), 064401 (2013).
[Crossref]

2011 (1)

A. M. Giovannozzi, V. E. V. Ferrero, F. Pennecchi, S. J. Sadeghi, G. Gilardi, and A. M. Rossi, “P450-based porous silicon biosensor for arachidonic acid detection,” Biosens. Bioelectron. 28(1), 320–325 (2011).
[Crossref] [PubMed]

2009 (2)

G. G. Rong and S. M. Weiss, “Biomolecule size‐dependent sensitivity of porous silicon sensors,” Phys. Status Solidi A 206(6), 1365–1368 (2009).
[Crossref]

D. R. Huanca, D. S. Raimundo, and W. J. Salcedo, “Backside contact effect on the morphological and optical features of porous silicon photonic crystals,” Microelectronics J. 40(4-5), 744–748 (2009).
[Crossref]

2007 (3)

I. A. Levitsky, W. B. Euler, N. Tokranova, and A. Rose, “Fluorescent polymer-porous silicon microcavity devices for explosive detection,” Appl. Phys. Lett. 90(4), 041904 (2007).
[Crossref]

H. Ouyang, L. A. Delouise, B. L. Miller, and P. M. Fauchet, “Label-free quantitative detection of protein using macroporous silicon photonic bandgap biosensors,” Anal. Chem. 79(4), 1502–1506 (2007).
[Crossref] [PubMed]

O. Meskini, A. Abdelghani, A. Tlili, R. Mgaieth, N. Jaffrezic-Renault, and C. Martelet, “Porous silicon as functionalized material for immunosensor application,” Talanta 71(3), 1430–1433 (2007).
[Crossref] [PubMed]

2006 (2)

S. P. Low, K. A. Williams, L. T. Canham, and N. H. Voelcker, “Evaluation of mammalian cell adhesion on surface-modified porous silicon,” Biomaterials 27(26), 4538–4546 (2006).
[Crossref] [PubMed]

D. C. Tessier, S. Boughaba, M. Arbour, P. Roos, and G. Pan, “Improved surface sensing of DNA on gas-etched porous silicon,” Sens. Actuators B Chem. 120(1), 220–230 (2006).
[Crossref]

2003 (2)

L. De Stefano, L. Moretti, I. Rendina, and A. M. Rossi, “Porous silicon microcavities for optical hydrocarbons detection,” Sens. Actuators A Phys. 104(2), 179–182 (2003).
[Crossref]

L. D. Stefano, I. Rendina, L. Moretti, and A. M. Rossi, “Optical sensing of flammable substances using porous silicon microcavities,” Mater. Sci. Eng. B 100(3), 271–274 (2003).
[Crossref]

2001 (1)

S. Chan, Y. Li, L. J. Rothberg, B. L. Miller, and P. M. Fauchet, “Nanoscale silicon microcavities for biosening,” Mater. Sci. Eng. C 15(1-2), 277–282 (2001).
[Crossref]

2000 (1)

S. Chan, P. M. Fauchet, Y. Li, L. J. Rothberg, and B. L. Miller, “Porous Silicon Microcavities for Biosensing Applications,” Phys. Status Solidi A 182(1), 541–546 (2000).
[Crossref]

1999 (1)

S. Chan and P. M. Fauchet, “Tunable, narrow, and directional luminescence from porous silicon light emtting devices,” Appl. Phys. Lett. 75(2), 274–276 (1999).
[Crossref]

1997 (1)

L. Pavesi, “Porous silicon dielectric multilayers and microcavities,” Riv. Nuovo Cim. 20(10), 1–76 (1997).
[Crossref]

Abdelghani, A.

O. Meskini, A. Abdelghani, A. Tlili, R. Mgaieth, N. Jaffrezic-Renault, and C. Martelet, “Porous silicon as functionalized material for immunosensor application,” Talanta 71(3), 1430–1433 (2007).
[Crossref] [PubMed]

Arbour, M.

D. C. Tessier, S. Boughaba, M. Arbour, P. Roos, and G. Pan, “Improved surface sensing of DNA on gas-etched porous silicon,” Sens. Actuators B Chem. 120(1), 220–230 (2006).
[Crossref]

Boughaba, S.

D. C. Tessier, S. Boughaba, M. Arbour, P. Roos, and G. Pan, “Improved surface sensing of DNA on gas-etched porous silicon,” Sens. Actuators B Chem. 120(1), 220–230 (2006).
[Crossref]

Canham, L. T.

S. P. Low, K. A. Williams, L. T. Canham, and N. H. Voelcker, “Evaluation of mammalian cell adhesion on surface-modified porous silicon,” Biomaterials 27(26), 4538–4546 (2006).
[Crossref] [PubMed]

Cao, Z.

X. Lü, F. Zhong, Z. Jia, L. Chen, J. Ma, H. Zhang, Z. Cao, and J. Zhou, “Development of silicon-on-insulator-based nanoporous silicon photonic crystals for label-free DNA detection,” Opt. Eng. 52(6), 064401 (2013).
[Crossref]

Chan, S.

S. Chan, Y. Li, L. J. Rothberg, B. L. Miller, and P. M. Fauchet, “Nanoscale silicon microcavities for biosening,” Mater. Sci. Eng. C 15(1-2), 277–282 (2001).
[Crossref]

S. Chan, P. M. Fauchet, Y. Li, L. J. Rothberg, and B. L. Miller, “Porous Silicon Microcavities for Biosensing Applications,” Phys. Status Solidi A 182(1), 541–546 (2000).
[Crossref]

S. Chan and P. M. Fauchet, “Tunable, narrow, and directional luminescence from porous silicon light emtting devices,” Appl. Phys. Lett. 75(2), 274–276 (1999).
[Crossref]

Chen, L.

X. Lü, L. Chen, H. Zhang, J. Mo, F. Zhong, C. Lv, J. Ma, and Z. Jia, “Hybridization assay of insect antifreezing protein gene by novel multilayered porous silicon nucleic acid biosensor,” Biosens. Bioelectron. 39(1), 329–333 (2013).
[Crossref] [PubMed]

H. Zhang, Z. Jia, X. Lü, J. Zhou, L. Chen, R. Liu, and J. Ma, “Porous silicon optical microcavity biosensor on silicon-on-insulator wafer for sensitive DNA detection,” Biosens. Bioelectron. 44, 89–94 (2013).
[Crossref] [PubMed]

X. Lü, F. Zhong, Z. Jia, L. Chen, J. Ma, H. Zhang, Z. Cao, and J. Zhou, “Development of silicon-on-insulator-based nanoporous silicon photonic crystals for label-free DNA detection,” Opt. Eng. 52(6), 064401 (2013).
[Crossref]

De Stefano, L.

L. De Stefano, L. Moretti, I. Rendina, and A. M. Rossi, “Porous silicon microcavities for optical hydrocarbons detection,” Sens. Actuators A Phys. 104(2), 179–182 (2003).
[Crossref]

Delouise, L. A.

H. Ouyang, L. A. Delouise, B. L. Miller, and P. M. Fauchet, “Label-free quantitative detection of protein using macroporous silicon photonic bandgap biosensors,” Anal. Chem. 79(4), 1502–1506 (2007).
[Crossref] [PubMed]

Euler, W. B.

I. A. Levitsky, W. B. Euler, N. Tokranova, and A. Rose, “Fluorescent polymer-porous silicon microcavity devices for explosive detection,” Appl. Phys. Lett. 90(4), 041904 (2007).
[Crossref]

Fauchet, P. M.

H. Ouyang, L. A. Delouise, B. L. Miller, and P. M. Fauchet, “Label-free quantitative detection of protein using macroporous silicon photonic bandgap biosensors,” Anal. Chem. 79(4), 1502–1506 (2007).
[Crossref] [PubMed]

S. Chan, Y. Li, L. J. Rothberg, B. L. Miller, and P. M. Fauchet, “Nanoscale silicon microcavities for biosening,” Mater. Sci. Eng. C 15(1-2), 277–282 (2001).
[Crossref]

S. Chan, P. M. Fauchet, Y. Li, L. J. Rothberg, and B. L. Miller, “Porous Silicon Microcavities for Biosensing Applications,” Phys. Status Solidi A 182(1), 541–546 (2000).
[Crossref]

S. Chan and P. M. Fauchet, “Tunable, narrow, and directional luminescence from porous silicon light emtting devices,” Appl. Phys. Lett. 75(2), 274–276 (1999).
[Crossref]

Ferrero, V. E. V.

A. M. Giovannozzi, V. E. V. Ferrero, F. Pennecchi, S. J. Sadeghi, G. Gilardi, and A. M. Rossi, “P450-based porous silicon biosensor for arachidonic acid detection,” Biosens. Bioelectron. 28(1), 320–325 (2011).
[Crossref] [PubMed]

Gilardi, G.

A. M. Giovannozzi, V. E. V. Ferrero, F. Pennecchi, S. J. Sadeghi, G. Gilardi, and A. M. Rossi, “P450-based porous silicon biosensor for arachidonic acid detection,” Biosens. Bioelectron. 28(1), 320–325 (2011).
[Crossref] [PubMed]

Giovannozzi, A. M.

A. M. Giovannozzi, V. E. V. Ferrero, F. Pennecchi, S. J. Sadeghi, G. Gilardi, and A. M. Rossi, “P450-based porous silicon biosensor for arachidonic acid detection,” Biosens. Bioelectron. 28(1), 320–325 (2011).
[Crossref] [PubMed]

He, T.

Y. M. Lai, J. Wang, T. He, and S. Sun, “Improved Surface Enhanced Raman Scattering for Nanostructured Silver on Porous Silicon for Ultrasensitive Determination of 2, 4, 6-Trinitrotoluene,” Anal. Lett. 47(5), 833–842 (2014).
[Crossref]

Hou, J.

H. Zhang, Z. Jia, X. Lü, J. Hou, X. Liu, J. Ma, and J. Zhou, “Antifreeze protein detection using Rhodamine B as photoluminescence label in porous silicon,” Curr. Appl. Phys. 13(4), 736–742 (2013).
[Crossref]

Huanca, D. R.

D. R. Huanca, D. S. Raimundo, and W. J. Salcedo, “Backside contact effect on the morphological and optical features of porous silicon photonic crystals,” Microelectronics J. 40(4-5), 744–748 (2009).
[Crossref]

Jaffrezic-Renault, N.

O. Meskini, A. Abdelghani, A. Tlili, R. Mgaieth, N. Jaffrezic-Renault, and C. Martelet, “Porous silicon as functionalized material for immunosensor application,” Talanta 71(3), 1430–1433 (2007).
[Crossref] [PubMed]

Jia, Z.

H. Zhang, Z. Jia, X. Lü, J. Hou, X. Liu, J. Ma, and J. Zhou, “Antifreeze protein detection using Rhodamine B as photoluminescence label in porous silicon,” Curr. Appl. Phys. 13(4), 736–742 (2013).
[Crossref]

X. Lü, L. Chen, H. Zhang, J. Mo, F. Zhong, C. Lv, J. Ma, and Z. Jia, “Hybridization assay of insect antifreezing protein gene by novel multilayered porous silicon nucleic acid biosensor,” Biosens. Bioelectron. 39(1), 329–333 (2013).
[Crossref] [PubMed]

H. Zhang, Z. Jia, X. Lü, J. Zhou, L. Chen, R. Liu, and J. Ma, “Porous silicon optical microcavity biosensor on silicon-on-insulator wafer for sensitive DNA detection,” Biosens. Bioelectron. 44, 89–94 (2013).
[Crossref] [PubMed]

X. Lü, F. Zhong, Z. Jia, L. Chen, J. Ma, H. Zhang, Z. Cao, and J. Zhou, “Development of silicon-on-insulator-based nanoporous silicon photonic crystals for label-free DNA detection,” Opt. Eng. 52(6), 064401 (2013).
[Crossref]

Krismastuti, F. S. H.

F. S. H. Krismastuti, S. Pace, and N. H. Voelcker, “Porous silicon resonant microcavity biosensor for matrix metalloproteinase detection,” Adv. Funct. Mater. 24(23), 3639–3650 (2014).

Lai, Y. M.

Y. M. Lai, J. Wang, T. He, and S. Sun, “Improved Surface Enhanced Raman Scattering for Nanostructured Silver on Porous Silicon for Ultrasensitive Determination of 2, 4, 6-Trinitrotoluene,” Anal. Lett. 47(5), 833–842 (2014).
[Crossref]

Levitsky, I. A.

I. A. Levitsky, W. B. Euler, N. Tokranova, and A. Rose, “Fluorescent polymer-porous silicon microcavity devices for explosive detection,” Appl. Phys. Lett. 90(4), 041904 (2007).
[Crossref]

Li, Y.

S. Chan, Y. Li, L. J. Rothberg, B. L. Miller, and P. M. Fauchet, “Nanoscale silicon microcavities for biosening,” Mater. Sci. Eng. C 15(1-2), 277–282 (2001).
[Crossref]

S. Chan, P. M. Fauchet, Y. Li, L. J. Rothberg, and B. L. Miller, “Porous Silicon Microcavities for Biosensing Applications,” Phys. Status Solidi A 182(1), 541–546 (2000).
[Crossref]

Liu, R.

H. Zhang, Z. Jia, X. Lü, J. Zhou, L. Chen, R. Liu, and J. Ma, “Porous silicon optical microcavity biosensor on silicon-on-insulator wafer for sensitive DNA detection,” Biosens. Bioelectron. 44, 89–94 (2013).
[Crossref] [PubMed]

Liu, X.

H. Zhang, Z. Jia, X. Lü, J. Hou, X. Liu, J. Ma, and J. Zhou, “Antifreeze protein detection using Rhodamine B as photoluminescence label in porous silicon,” Curr. Appl. Phys. 13(4), 736–742 (2013).
[Crossref]

Low, S. P.

S. P. Low, K. A. Williams, L. T. Canham, and N. H. Voelcker, “Evaluation of mammalian cell adhesion on surface-modified porous silicon,” Biomaterials 27(26), 4538–4546 (2006).
[Crossref] [PubMed]

Lü, X.

H. Zhang, Z. Jia, X. Lü, J. Hou, X. Liu, J. Ma, and J. Zhou, “Antifreeze protein detection using Rhodamine B as photoluminescence label in porous silicon,” Curr. Appl. Phys. 13(4), 736–742 (2013).
[Crossref]

X. Lü, L. Chen, H. Zhang, J. Mo, F. Zhong, C. Lv, J. Ma, and Z. Jia, “Hybridization assay of insect antifreezing protein gene by novel multilayered porous silicon nucleic acid biosensor,” Biosens. Bioelectron. 39(1), 329–333 (2013).
[Crossref] [PubMed]

H. Zhang, Z. Jia, X. Lü, J. Zhou, L. Chen, R. Liu, and J. Ma, “Porous silicon optical microcavity biosensor on silicon-on-insulator wafer for sensitive DNA detection,” Biosens. Bioelectron. 44, 89–94 (2013).
[Crossref] [PubMed]

X. Lü, F. Zhong, Z. Jia, L. Chen, J. Ma, H. Zhang, Z. Cao, and J. Zhou, “Development of silicon-on-insulator-based nanoporous silicon photonic crystals for label-free DNA detection,” Opt. Eng. 52(6), 064401 (2013).
[Crossref]

Lv, C.

X. Lü, L. Chen, H. Zhang, J. Mo, F. Zhong, C. Lv, J. Ma, and Z. Jia, “Hybridization assay of insect antifreezing protein gene by novel multilayered porous silicon nucleic acid biosensor,” Biosens. Bioelectron. 39(1), 329–333 (2013).
[Crossref] [PubMed]

Ma, J.

X. Lü, L. Chen, H. Zhang, J. Mo, F. Zhong, C. Lv, J. Ma, and Z. Jia, “Hybridization assay of insect antifreezing protein gene by novel multilayered porous silicon nucleic acid biosensor,” Biosens. Bioelectron. 39(1), 329–333 (2013).
[Crossref] [PubMed]

H. Zhang, Z. Jia, X. Lü, J. Hou, X. Liu, J. Ma, and J. Zhou, “Antifreeze protein detection using Rhodamine B as photoluminescence label in porous silicon,” Curr. Appl. Phys. 13(4), 736–742 (2013).
[Crossref]

X. Lü, F. Zhong, Z. Jia, L. Chen, J. Ma, H. Zhang, Z. Cao, and J. Zhou, “Development of silicon-on-insulator-based nanoporous silicon photonic crystals for label-free DNA detection,” Opt. Eng. 52(6), 064401 (2013).
[Crossref]

H. Zhang, Z. Jia, X. Lü, J. Zhou, L. Chen, R. Liu, and J. Ma, “Porous silicon optical microcavity biosensor on silicon-on-insulator wafer for sensitive DNA detection,” Biosens. Bioelectron. 44, 89–94 (2013).
[Crossref] [PubMed]

Martelet, C.

O. Meskini, A. Abdelghani, A. Tlili, R. Mgaieth, N. Jaffrezic-Renault, and C. Martelet, “Porous silicon as functionalized material for immunosensor application,” Talanta 71(3), 1430–1433 (2007).
[Crossref] [PubMed]

Meskini, O.

O. Meskini, A. Abdelghani, A. Tlili, R. Mgaieth, N. Jaffrezic-Renault, and C. Martelet, “Porous silicon as functionalized material for immunosensor application,” Talanta 71(3), 1430–1433 (2007).
[Crossref] [PubMed]

Mgaieth, R.

O. Meskini, A. Abdelghani, A. Tlili, R. Mgaieth, N. Jaffrezic-Renault, and C. Martelet, “Porous silicon as functionalized material for immunosensor application,” Talanta 71(3), 1430–1433 (2007).
[Crossref] [PubMed]

Miller, B. L.

H. Ouyang, L. A. Delouise, B. L. Miller, and P. M. Fauchet, “Label-free quantitative detection of protein using macroporous silicon photonic bandgap biosensors,” Anal. Chem. 79(4), 1502–1506 (2007).
[Crossref] [PubMed]

S. Chan, Y. Li, L. J. Rothberg, B. L. Miller, and P. M. Fauchet, “Nanoscale silicon microcavities for biosening,” Mater. Sci. Eng. C 15(1-2), 277–282 (2001).
[Crossref]

S. Chan, P. M. Fauchet, Y. Li, L. J. Rothberg, and B. L. Miller, “Porous Silicon Microcavities for Biosensing Applications,” Phys. Status Solidi A 182(1), 541–546 (2000).
[Crossref]

Mo, J.

X. Lü, L. Chen, H. Zhang, J. Mo, F. Zhong, C. Lv, J. Ma, and Z. Jia, “Hybridization assay of insect antifreezing protein gene by novel multilayered porous silicon nucleic acid biosensor,” Biosens. Bioelectron. 39(1), 329–333 (2013).
[Crossref] [PubMed]

Moretti, L.

L. D. Stefano, I. Rendina, L. Moretti, and A. M. Rossi, “Optical sensing of flammable substances using porous silicon microcavities,” Mater. Sci. Eng. B 100(3), 271–274 (2003).
[Crossref]

L. De Stefano, L. Moretti, I. Rendina, and A. M. Rossi, “Porous silicon microcavities for optical hydrocarbons detection,” Sens. Actuators A Phys. 104(2), 179–182 (2003).
[Crossref]

Ouyang, H.

H. Ouyang, L. A. Delouise, B. L. Miller, and P. M. Fauchet, “Label-free quantitative detection of protein using macroporous silicon photonic bandgap biosensors,” Anal. Chem. 79(4), 1502–1506 (2007).
[Crossref] [PubMed]

Pace, S.

F. S. H. Krismastuti, S. Pace, and N. H. Voelcker, “Porous silicon resonant microcavity biosensor for matrix metalloproteinase detection,” Adv. Funct. Mater. 24(23), 3639–3650 (2014).

Pan, G.

D. C. Tessier, S. Boughaba, M. Arbour, P. Roos, and G. Pan, “Improved surface sensing of DNA on gas-etched porous silicon,” Sens. Actuators B Chem. 120(1), 220–230 (2006).
[Crossref]

Pavesi, L.

L. Pavesi, “Porous silicon dielectric multilayers and microcavities,” Riv. Nuovo Cim. 20(10), 1–76 (1997).
[Crossref]

Pennecchi, F.

A. M. Giovannozzi, V. E. V. Ferrero, F. Pennecchi, S. J. Sadeghi, G. Gilardi, and A. M. Rossi, “P450-based porous silicon biosensor for arachidonic acid detection,” Biosens. Bioelectron. 28(1), 320–325 (2011).
[Crossref] [PubMed]

Raimundo, D. S.

D. R. Huanca, D. S. Raimundo, and W. J. Salcedo, “Backside contact effect on the morphological and optical features of porous silicon photonic crystals,” Microelectronics J. 40(4-5), 744–748 (2009).
[Crossref]

Rendina, I.

L. De Stefano, L. Moretti, I. Rendina, and A. M. Rossi, “Porous silicon microcavities for optical hydrocarbons detection,” Sens. Actuators A Phys. 104(2), 179–182 (2003).
[Crossref]

L. D. Stefano, I. Rendina, L. Moretti, and A. M. Rossi, “Optical sensing of flammable substances using porous silicon microcavities,” Mater. Sci. Eng. B 100(3), 271–274 (2003).
[Crossref]

Rong, G. G.

G. G. Rong and S. M. Weiss, “Biomolecule size‐dependent sensitivity of porous silicon sensors,” Phys. Status Solidi A 206(6), 1365–1368 (2009).
[Crossref]

Roos, P.

D. C. Tessier, S. Boughaba, M. Arbour, P. Roos, and G. Pan, “Improved surface sensing of DNA on gas-etched porous silicon,” Sens. Actuators B Chem. 120(1), 220–230 (2006).
[Crossref]

Rose, A.

I. A. Levitsky, W. B. Euler, N. Tokranova, and A. Rose, “Fluorescent polymer-porous silicon microcavity devices for explosive detection,” Appl. Phys. Lett. 90(4), 041904 (2007).
[Crossref]

Rossi, A. M.

A. M. Giovannozzi, V. E. V. Ferrero, F. Pennecchi, S. J. Sadeghi, G. Gilardi, and A. M. Rossi, “P450-based porous silicon biosensor for arachidonic acid detection,” Biosens. Bioelectron. 28(1), 320–325 (2011).
[Crossref] [PubMed]

L. De Stefano, L. Moretti, I. Rendina, and A. M. Rossi, “Porous silicon microcavities for optical hydrocarbons detection,” Sens. Actuators A Phys. 104(2), 179–182 (2003).
[Crossref]

L. D. Stefano, I. Rendina, L. Moretti, and A. M. Rossi, “Optical sensing of flammable substances using porous silicon microcavities,” Mater. Sci. Eng. B 100(3), 271–274 (2003).
[Crossref]

Rothberg, L. J.

S. Chan, Y. Li, L. J. Rothberg, B. L. Miller, and P. M. Fauchet, “Nanoscale silicon microcavities for biosening,” Mater. Sci. Eng. C 15(1-2), 277–282 (2001).
[Crossref]

S. Chan, P. M. Fauchet, Y. Li, L. J. Rothberg, and B. L. Miller, “Porous Silicon Microcavities for Biosensing Applications,” Phys. Status Solidi A 182(1), 541–546 (2000).
[Crossref]

Sadeghi, S. J.

A. M. Giovannozzi, V. E. V. Ferrero, F. Pennecchi, S. J. Sadeghi, G. Gilardi, and A. M. Rossi, “P450-based porous silicon biosensor for arachidonic acid detection,” Biosens. Bioelectron. 28(1), 320–325 (2011).
[Crossref] [PubMed]

Salcedo, W. J.

D. R. Huanca, D. S. Raimundo, and W. J. Salcedo, “Backside contact effect on the morphological and optical features of porous silicon photonic crystals,” Microelectronics J. 40(4-5), 744–748 (2009).
[Crossref]

Stefano, L. D.

L. D. Stefano, I. Rendina, L. Moretti, and A. M. Rossi, “Optical sensing of flammable substances using porous silicon microcavities,” Mater. Sci. Eng. B 100(3), 271–274 (2003).
[Crossref]

Sun, S.

Y. M. Lai, J. Wang, T. He, and S. Sun, “Improved Surface Enhanced Raman Scattering for Nanostructured Silver on Porous Silicon for Ultrasensitive Determination of 2, 4, 6-Trinitrotoluene,” Anal. Lett. 47(5), 833–842 (2014).
[Crossref]

Tessier, D. C.

D. C. Tessier, S. Boughaba, M. Arbour, P. Roos, and G. Pan, “Improved surface sensing of DNA on gas-etched porous silicon,” Sens. Actuators B Chem. 120(1), 220–230 (2006).
[Crossref]

Tlili, A.

O. Meskini, A. Abdelghani, A. Tlili, R. Mgaieth, N. Jaffrezic-Renault, and C. Martelet, “Porous silicon as functionalized material for immunosensor application,” Talanta 71(3), 1430–1433 (2007).
[Crossref] [PubMed]

Tokranova, N.

I. A. Levitsky, W. B. Euler, N. Tokranova, and A. Rose, “Fluorescent polymer-porous silicon microcavity devices for explosive detection,” Appl. Phys. Lett. 90(4), 041904 (2007).
[Crossref]

Voelcker, N. H.

F. S. H. Krismastuti, S. Pace, and N. H. Voelcker, “Porous silicon resonant microcavity biosensor for matrix metalloproteinase detection,” Adv. Funct. Mater. 24(23), 3639–3650 (2014).

S. P. Low, K. A. Williams, L. T. Canham, and N. H. Voelcker, “Evaluation of mammalian cell adhesion on surface-modified porous silicon,” Biomaterials 27(26), 4538–4546 (2006).
[Crossref] [PubMed]

Wang, J.

Y. M. Lai, J. Wang, T. He, and S. Sun, “Improved Surface Enhanced Raman Scattering for Nanostructured Silver on Porous Silicon for Ultrasensitive Determination of 2, 4, 6-Trinitrotoluene,” Anal. Lett. 47(5), 833–842 (2014).
[Crossref]

Weiss, S. M.

G. G. Rong and S. M. Weiss, “Biomolecule size‐dependent sensitivity of porous silicon sensors,” Phys. Status Solidi A 206(6), 1365–1368 (2009).
[Crossref]

Williams, K. A.

S. P. Low, K. A. Williams, L. T. Canham, and N. H. Voelcker, “Evaluation of mammalian cell adhesion on surface-modified porous silicon,” Biomaterials 27(26), 4538–4546 (2006).
[Crossref] [PubMed]

Zhang, H.

H. Zhang, Z. Jia, X. Lü, J. Hou, X. Liu, J. Ma, and J. Zhou, “Antifreeze protein detection using Rhodamine B as photoluminescence label in porous silicon,” Curr. Appl. Phys. 13(4), 736–742 (2013).
[Crossref]

X. Lü, L. Chen, H. Zhang, J. Mo, F. Zhong, C. Lv, J. Ma, and Z. Jia, “Hybridization assay of insect antifreezing protein gene by novel multilayered porous silicon nucleic acid biosensor,” Biosens. Bioelectron. 39(1), 329–333 (2013).
[Crossref] [PubMed]

H. Zhang, Z. Jia, X. Lü, J. Zhou, L. Chen, R. Liu, and J. Ma, “Porous silicon optical microcavity biosensor on silicon-on-insulator wafer for sensitive DNA detection,” Biosens. Bioelectron. 44, 89–94 (2013).
[Crossref] [PubMed]

X. Lü, F. Zhong, Z. Jia, L. Chen, J. Ma, H. Zhang, Z. Cao, and J. Zhou, “Development of silicon-on-insulator-based nanoporous silicon photonic crystals for label-free DNA detection,” Opt. Eng. 52(6), 064401 (2013).
[Crossref]

Zhong, F.

X. Lü, F. Zhong, Z. Jia, L. Chen, J. Ma, H. Zhang, Z. Cao, and J. Zhou, “Development of silicon-on-insulator-based nanoporous silicon photonic crystals for label-free DNA detection,” Opt. Eng. 52(6), 064401 (2013).
[Crossref]

X. Lü, L. Chen, H. Zhang, J. Mo, F. Zhong, C. Lv, J. Ma, and Z. Jia, “Hybridization assay of insect antifreezing protein gene by novel multilayered porous silicon nucleic acid biosensor,” Biosens. Bioelectron. 39(1), 329–333 (2013).
[Crossref] [PubMed]

Zhou, J.

H. Zhang, Z. Jia, X. Lü, J. Hou, X. Liu, J. Ma, and J. Zhou, “Antifreeze protein detection using Rhodamine B as photoluminescence label in porous silicon,” Curr. Appl. Phys. 13(4), 736–742 (2013).
[Crossref]

H. Zhang, Z. Jia, X. Lü, J. Zhou, L. Chen, R. Liu, and J. Ma, “Porous silicon optical microcavity biosensor on silicon-on-insulator wafer for sensitive DNA detection,” Biosens. Bioelectron. 44, 89–94 (2013).
[Crossref] [PubMed]

X. Lü, F. Zhong, Z. Jia, L. Chen, J. Ma, H. Zhang, Z. Cao, and J. Zhou, “Development of silicon-on-insulator-based nanoporous silicon photonic crystals for label-free DNA detection,” Opt. Eng. 52(6), 064401 (2013).
[Crossref]

Adv. Funct. Mater. (1)

F. S. H. Krismastuti, S. Pace, and N. H. Voelcker, “Porous silicon resonant microcavity biosensor for matrix metalloproteinase detection,” Adv. Funct. Mater. 24(23), 3639–3650 (2014).

Anal. Chem. (1)

H. Ouyang, L. A. Delouise, B. L. Miller, and P. M. Fauchet, “Label-free quantitative detection of protein using macroporous silicon photonic bandgap biosensors,” Anal. Chem. 79(4), 1502–1506 (2007).
[Crossref] [PubMed]

Anal. Lett. (1)

Y. M. Lai, J. Wang, T. He, and S. Sun, “Improved Surface Enhanced Raman Scattering for Nanostructured Silver on Porous Silicon for Ultrasensitive Determination of 2, 4, 6-Trinitrotoluene,” Anal. Lett. 47(5), 833–842 (2014).
[Crossref]

Appl. Phys. Lett. (2)

S. Chan and P. M. Fauchet, “Tunable, narrow, and directional luminescence from porous silicon light emtting devices,” Appl. Phys. Lett. 75(2), 274–276 (1999).
[Crossref]

I. A. Levitsky, W. B. Euler, N. Tokranova, and A. Rose, “Fluorescent polymer-porous silicon microcavity devices for explosive detection,” Appl. Phys. Lett. 90(4), 041904 (2007).
[Crossref]

Biomaterials (1)

S. P. Low, K. A. Williams, L. T. Canham, and N. H. Voelcker, “Evaluation of mammalian cell adhesion on surface-modified porous silicon,” Biomaterials 27(26), 4538–4546 (2006).
[Crossref] [PubMed]

Biosens. Bioelectron. (3)

A. M. Giovannozzi, V. E. V. Ferrero, F. Pennecchi, S. J. Sadeghi, G. Gilardi, and A. M. Rossi, “P450-based porous silicon biosensor for arachidonic acid detection,” Biosens. Bioelectron. 28(1), 320–325 (2011).
[Crossref] [PubMed]

X. Lü, L. Chen, H. Zhang, J. Mo, F. Zhong, C. Lv, J. Ma, and Z. Jia, “Hybridization assay of insect antifreezing protein gene by novel multilayered porous silicon nucleic acid biosensor,” Biosens. Bioelectron. 39(1), 329–333 (2013).
[Crossref] [PubMed]

H. Zhang, Z. Jia, X. Lü, J. Zhou, L. Chen, R. Liu, and J. Ma, “Porous silicon optical microcavity biosensor on silicon-on-insulator wafer for sensitive DNA detection,” Biosens. Bioelectron. 44, 89–94 (2013).
[Crossref] [PubMed]

Curr. Appl. Phys. (1)

H. Zhang, Z. Jia, X. Lü, J. Hou, X. Liu, J. Ma, and J. Zhou, “Antifreeze protein detection using Rhodamine B as photoluminescence label in porous silicon,” Curr. Appl. Phys. 13(4), 736–742 (2013).
[Crossref]

Mater. Sci. Eng. B (1)

L. D. Stefano, I. Rendina, L. Moretti, and A. M. Rossi, “Optical sensing of flammable substances using porous silicon microcavities,” Mater. Sci. Eng. B 100(3), 271–274 (2003).
[Crossref]

Mater. Sci. Eng. C (1)

S. Chan, Y. Li, L. J. Rothberg, B. L. Miller, and P. M. Fauchet, “Nanoscale silicon microcavities for biosening,” Mater. Sci. Eng. C 15(1-2), 277–282 (2001).
[Crossref]

Microelectronics J. (1)

D. R. Huanca, D. S. Raimundo, and W. J. Salcedo, “Backside contact effect on the morphological and optical features of porous silicon photonic crystals,” Microelectronics J. 40(4-5), 744–748 (2009).
[Crossref]

Opt. Eng. (1)

X. Lü, F. Zhong, Z. Jia, L. Chen, J. Ma, H. Zhang, Z. Cao, and J. Zhou, “Development of silicon-on-insulator-based nanoporous silicon photonic crystals for label-free DNA detection,” Opt. Eng. 52(6), 064401 (2013).
[Crossref]

Phys. Status Solidi A (2)

S. Chan, P. M. Fauchet, Y. Li, L. J. Rothberg, and B. L. Miller, “Porous Silicon Microcavities for Biosensing Applications,” Phys. Status Solidi A 182(1), 541–546 (2000).
[Crossref]

G. G. Rong and S. M. Weiss, “Biomolecule size‐dependent sensitivity of porous silicon sensors,” Phys. Status Solidi A 206(6), 1365–1368 (2009).
[Crossref]

Riv. Nuovo Cim. (1)

L. Pavesi, “Porous silicon dielectric multilayers and microcavities,” Riv. Nuovo Cim. 20(10), 1–76 (1997).
[Crossref]

Sens. Actuators A Phys. (1)

L. De Stefano, L. Moretti, I. Rendina, and A. M. Rossi, “Porous silicon microcavities for optical hydrocarbons detection,” Sens. Actuators A Phys. 104(2), 179–182 (2003).
[Crossref]

Sens. Actuators B Chem. (1)

D. C. Tessier, S. Boughaba, M. Arbour, P. Roos, and G. Pan, “Improved surface sensing of DNA on gas-etched porous silicon,” Sens. Actuators B Chem. 120(1), 220–230 (2006).
[Crossref]

Talanta (1)

O. Meskini, A. Abdelghani, A. Tlili, R. Mgaieth, N. Jaffrezic-Renault, and C. Martelet, “Porous silicon as functionalized material for immunosensor application,” Talanta 71(3), 1430–1433 (2007).
[Crossref] [PubMed]

Other (2)

X. Y. Lü, T. Xue, Z. H.Jia, H. W. Shao, S. B. Hou, and F. C. Zhang, “Design and Realization of Label-free Optical Immunosensor Based on Porous Silicon Microcavities,” In Society of Photo-Optical Instrumentation Engineers (SPIE) Conference Series, (Academic 2008), pp. 71571E–71571E.

G.G.Rong, J.D. Ryckman, R.L.Mernaugh, and S.M.Weiss, “Label-free porous silicon membrane waveguide for DNA sensing,” Appl. Phys. Lett. 93(16), 161109–161109, 1–3(2008).
[Crossref]

Cited By

OSA participates in Crossref's Cited-By Linking service. Citing articles from OSA journals and other participating publishers are listed here.

Alert me when this article is cited.


Figures (6)

Fig. 1
Fig. 1 (a) PSM reflection spectra of incident angles θ = 0°, 10°, 20° and 30°, respectively; (b) Curve (a) represents the PSM reflection spectrum of vertical incidence (θ = 0°). Curve (b) represents the occurrence of a biological reaction in the PSM device, causing the refractive index to increase Δn = 0.01, and represents an identical PSM reflection spectrum to vertical incidence (θ = 0°). Curve (c) represents the PSM reflection spectrum after a certain rotary angle of incident light.
Fig. 2
Fig. 2 The forbidden band diagram of TE mode according to incidence angle.
Fig. 3
Fig. 3 SEM images of PSM. (a) top view; (b) cross-section.
Fig. 4
Fig. 4 Experimental apparatus and sample structure.
Fig. 5
Fig. 5 (a) Angle spectra corresponding with changes in the PSM functional steps: after oxidation, silanization, and addition of glutaraldehyde. (b) The PSM angle spectra changes for complementary DNA. (c) Negligible PSM angle spectra changes for non-complementary DNA. (d) No change in the PSM angle spectra in reaction to buffer solution.
Fig. 6
Fig. 6 Linear relationship diagram for angle spectrum changes with the concentration of DNA from 0.3125 to 10 μM.

Metrics